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Scleroderma

Scleroderma is a multisystem disorder characterized by inflammatory, vascular, and sclerotic changes of the skin and various internal organs, especially the lungs, heart, and GI tract.

Causes of Scleroderma

Although the cause is unknown, it is known that the body produces too much of a protein called collagen. Excess collagen is deposited causing thickening and hardening.

Symptoms of Scleroderma

Signs and symptoms may include:

• Numbness, pain or color changes in your fingers, toes, cheeks, nose and ears, often brought on by cold or emotional distress (Raynaud's phenomenon)
• Digestive problems ranging from poor absorption of nutrients to delayed movement of food due to impaired muscular activity in your intestine
• Puffy hands and feet, particularly in the morning

Diagnosis

Physical exam, medical history and lab tests which may include biopsy and blood tests. Scleroderma can be difficult to diagnose. It's rare and, early on, it can affect the skin as well as the joints, making it look like other diseases.

To make a diagnosis, your doctor reviews your medical history and conducts a physical examination. As part of the examination, your doctor looks at your skin, checking for thickened and hardened areas. Your doctor may also examine and touch some of your joints and tendons to check for possible changes in connective tissue beneath your skin.

Treatment

Treatments may include:

• Medications: NSAIDs/aspirin for inflammation and pain, steroids to treat muscle/joint problems, antacids to reduce heartburn, medication to control blood pressure and to increase blood flow
• Exercise to improve overall health.